Recent publications

arising from Anatomical Society sponsored research

Society sponsored post-graduate students, undergraduate vacation students and principal investigators marked in bold italic, italic and bold.

Alhindi A, Boehm I, Chaytow, H (2021) Small junction, big problems; neuromuscular junction pathology in mouse models of amyotrophic lateral sclerosis (ALS) (2021) Journal of Anatomy, epub ahead of print ,DOI: 10.1111/joa.13463 

Watson KS, Boukhloufi I, Bowerman M, Parson SH (2021) The relationship between body composition, fatty acid metabolism, and diet in spinal muscular atrophy . Brain Sciences,11,131.   DOI: 10.3390/brainsci11020131

Shepherd RF,  
Kerns JG, Ranganath LR, Gallagher JA, Taylor AM (2021) Lessons from rare forms of osteoarthritis. Calcified Tissue International, 109, 291-302. DOI:10.1007/s00223-021-00896-3

Chatzeli L
, Teshima THN, Hajihosseini MK, Gaete M, Proctor GB, Tucker AS (2021) Comparing development and regeneration in the submandibular gland highlights distinct mechanisms. Journal of Anatomy 238, 1371-1385 DOI: 10.1111/joa.13387

Usansky I
, Jaworska P, Asti L, Kenny FN, Hobbs C, Sofra V, Song HF, Logan M, Graham A, Shaw TJ (2020) A developmental basis for the anatomical diversity of dermis in homeostasis and wound repair. Journal of Pathology epub ahead of print doi.pdfdirect/10.1002/path.5589 

Fons JM, Mozzafari M, Malik D, Marshall AR, Connor S, Greene NDE, Tucker AS (2020) Epithelial dynamics shed light on mechanisms underlying ear canal deficits. Development 147, dev194654. DOI: 10.1242/dev.194654

Frost M, Keable A, Baseley D, Sealy A, Zbarcea DA, Gatherer M, Yuen HM, Sharp MM, Weller RO, Attems JA, Smith C, Chiarot PR, Carare RO (2020) Vascular alpha 1A adrenergic receptors as a potential therapeutic target for IPAD in Alzheimer's disease. Pharmaceuticals 13, 261. 

DOI: 10.3390/ph13090261

Boehm I,  Alhindi A, Leite AS, Logie C, Gibbs A, Murray O, Farrukh R, Pirie R, Proudfoot C, Clutton R, Wishart TM, Jones RA, Gillingwater TH (2020) Comparative anatomy of the mammalian neuromuscular junction. Journal of Anatomy 237: 827-836

Elton S, Dunn J (2020) Baboon biogeography, divergence, and evolution: morphological and paleoecological prespectives. Journal of Human Evolution, 145, 102799. DOI: 10.1016/j.jhevol.2020.102799

Hoyle HW, Smith LA, Williams RJ, Przyborski SA (2020) Applications of novel bioreactor technology to enhance the viability and function of cultured cells and tissues. Interface Focus, 10, 20190090. 

DOI: 10.1098/rsfs.2019.0090.

Cook GWM, Sousa C, Schaeffer J, Wiles K, Jareonsettasin P, Kalyansundaram A, Walder E, Casper C, Patel S, Chua PW, Riboni-Verri G, Raza, M, Swaddiwudhipong N, Hui A, Abdullah A, Waied S, Keynes RJ (2020) Regulation of nerve growth and patterning by cell surface protein disulphide isomerase. Elife, 9 e54612.

Ratie L, Desmaris E, Garcia-Moreno F, Hoerder-Suabedissen A, Kelman A, Theil T, Bellefroid EJ, Molnar Z (2020) Loss of Dmrt5 affects the formation of the subplate and early corticogenesis. Cerebral Cortex, 30, 3296-3312.

Mole AJ, Bell S, Thomson AK, Dissanayake KN, Ribchester RR, Murray LM (2020) Synaptic withdrawal following nerve injury is influenced by postnatal maturity, muscle specific properties, and the presence of underlying pathology in mice. Journal of Anatomy, 237, 263-274.

Gallagher LB, Dolan EB, O'Sullivan J, Levey R, Cavanagh BL, Kovarova L, Pravda M, Velebny V, Farrell T, O'Brien FJ, Duffy GP (2020) Acta Biomaterialia, 107, 78-90. DOI   10.1016/j.actbio.2020.02.043

Allardyce H, Kuhn D, Hernandez-Gerez E, Hensel N, Huang YT, Faller K, Gillingwater TH, Quondamatteo F, Claus P, Parson SH. (2020)  Renal pathology in a mouse model of severe Spinal Muscular Atrophy is associated with downregulation of Glial Cell-Line Derived Neurotrophic Factor (GDNF). Human Molecular Genetics, 29, 2365-2378.  DOI: 10.1093/hmg/ddaa126

Matthan J, Cobb M, McHanwell S, Moxham B, Finn GM  (2020) The Anatomical Society's core syllabus for dental undergraduates. Journal of Anatomy, 236, 737-751. 

Lee, TC (2020) Anatomy and acadamies of art II – a tale of two cities. Journal of Anatomy, Epub ahead of print, DOI: 10.1111/joa.13130

Parnall M, Perdios C, Pang KL, Rochette S, Loughna S (2019) Characterisation of the developing heart in a pressure overloaded model utilising RNA sequencing to direct functional analysis. Journal of Anatomy, epub ahead of print DOI: 10.1111/joa.13112

Holland JC, Smith C, O’Shea M, Stewart J, Ockleford C, Finn GM (2019) The anatomical society core embryology syllabus for undergraduate medicine. Journal of Anatomy, 235, 847-860.  DOI: 10.1111/joa.13023

Šoltić D, Shorrock HK, Allardyce H, Wilson EL, Holt I, Synowsky SA, Shirran SL, Parson SH, Gillingwater TH, Fuller HR (2019) Lamini A/C dysregulation contributes to cardiac pathology in a mouse model of severe spinal muscular atrophy. Human Molecular Genetics, 28, 3515-3527. DOI: 10.1093/hmg/ddz195

Smith CF, Finn GM, Hennessy C, Luscombe C, Stewart J, McHanwell S (2019) The Initial Impact of the Anatomical Society Gross Anatomy Core Syllabus for Medicine in the United Kingdom: Student and Teacher Perspectives. Anatomical Sciences Education, 12, 494-506. DOI: 10.1002/ase.1826

Courtney NL, Mole AJ, Thomson AK, Murray LM (2019) Reduced P53 levels ameliorate neuromuscular junction loss without affecting motor neuron pathology in a mouse model of spinal muscular atrophy. Cell Death and Disease, 10, 515. DOI: 10.1038/s41419-019-1727-6 

Armstrong NC, Anderson RC, McDermott KW (2019) Reelin: diverse roles in central nervous system development, health and disease. International Journal of Biochemistry and Cell Bioilogy 112, 72-75.  DOI: 10.1016/j.biocel.2019.04.009

McGonnell IM, Akbareian SE (2019) Like a hole in the head: Development, evolutionary implications and diseases of the cranial foramina. Seminars in Cell and Developmental Biology, 91, 23-30. DOI:10.1016/j.semcdb.2018.08.011

Perdios C, Parnall M, Pang KL, Loughna S (2019) Altered haemodynamics causes aberrations in the epicardium. Journal of Anatomy, 234, 800-814. DOI:

Berneau SC, Ruane PT, Brison DR, Kimber SJ, Westwood M, Aplin JD (2019) Investigating the role of CD44 and hyaluronate in embryo-epithelial interaction using an in vitro model. Molecular Human Reproduction, 25, 265-273. DOI: 10.1093/molehr/gaz011

Berneau SC, Ruane PT, Brison DR, Kimber SJ, Westwood M, Aplin JD (2019) Characterisation of Osteopontin in an In Vitro Model of Embryo Implantation. Cells, 8, 432. DOI: 10.3390/cells8050432  

Panzica DA, Findlay AS, van Ladesteijn R, Collinson JM (2019) The core planar cell polarity gene, Vangl2, maintains apical-basal organisation of the corneal epithelium. Journal of Anatomy, 234, 106-119. DOI: 10.1111/joa.1267.

Sahrunizam K, Oddy C, Basson AM (2018) Autism-linked CHD gene expression patterns during development predict multi-organ diseased phenotypes. Journal of Anatomy 233, 755-769.
DOI: 10.1111/joa.12889

Ruane PT, Koeck R, Berneau SC, Kimber SJ, Westwood M, Brison DR, Aplin JD (2018) Osmotic stress induces JNK-dependent embryo invasion in a model of implantation. Reproduction 156, 421-428. 
DOI: 10.1530/REP-18-0154 

Jevans B, McCann CJ, Thapar N, Burns AJ (2018) Transplanted enteric neural stem cells integrate with the developing chick spinal cord: implications for spinal cord repair. Journal of Anatomy, 233, 592-606. DOI: 10.1111/joa.12880.

Kumar A, Davies TG, Itasaki N (2018) Developmental abnormalities of otic capsule and inner ear following application of prolyl-hydroxylase inhibitors in chick embryos. Birth Defects Research, 110, 1194-1204. DOI: 10.1002/bdr2.1375.

Miller SR, Benito C, Mirsky R, Jessen KR, Baker CVH (2018) Neural crest Notch/Rbpj signalling regulates olfactory gliogenesis and neuronal maturation. Genesis. 56 e23215 PMCID PMC6099236

Clowry GJ, Alzu’bi A, Harkin LF, Sarma S, Kerwin J, Lindsay SJ (2018) Charting the protomap of the human telencephalon. Seminars in Cell and Developmental Biology. 76, 3-14.
DOI: 10.1016/j.semcdb.2017.08.033 

Collinson, JM, Lindstrom, NO, Neves C, Wallace K, Meharg C, Charles RH, Ross ZK, Fraser AM, Mbogo I, Oras K, Nakamoto M, Barker S, Duce S, Miedzybrodzka Z, Vargesson N. 2018. The developmental and genetic basis of ‘clubfoot’ in the peroneal muscular atrophy mouse. Development 145: UNSP dev160093  DOI: 10.1242/dev.160093. PUBMED 29439133.

Connolly SA, Gillingwater TH, Chandler C, Grant AW, Greig J, Meskell M, Ross MT, Smith CF, Wood AF, Finn GM (2018) The Anatomical Society’s core syllabus for undergraduate nursing. Journal of Anatomy,  232, 721-728. DOI: 10.1111/joa.12782 

Whittaker DE, Kasah S, Donovan APA, Ellegood J, Riegman KLH, Volk, HA, McGonnell I,  Lerch JP,   Basson MA (2017) Distinct cerebellar foliation anomalies in a CHD7 haploinsufficient mouse model of CHARGE syndrome. American Journal of Medical Genetics (part c-seminars in medical genetics) 175, 465-477. DOI 10.1002/ajmg.c.31595

Espinosa-MeDOIna I,  Jevans B,  Boismoreau F, Chettouh Z, Enomoto H, Muller T, Birchmeier C, Burns A, Brunet JF (2017) Dual origin of enteric neurons in vagal Schwann cell precursors and the sympathetic neural crest. Proceedings of the National Academy of Sciences (USA) 114, 11980-11985. 
DOI 10.1073/pnas.1710308114. PUBMED 29078343.

Donovan AP,  Yu T, Ellegood J,  Riegman KLH, de Geus C, van Ravenswaaij-Arts C, Fernandes C, Lerch JP, Basson MA (2017) Cerebellar vermis and midbrain hypoplasia upon conditional deletion of chd7 from the embryonic mid-hindbrain region. Frontiers in Neuroanatomy 11, 86.
DOI 10.3389/fnana.2017.00086. PUBMED 29046629.

Alzu'bi A, Lindsay SJ, Harkin LF, McIntyre J, Lisgo SN, Clowry GJ (2017) The transcription factors COUP-TFI and COUP-TFII have distinct roles in arealisation and GABAergic interneuron specification in the early human fetal telencephalon. Cerebral Cortex 27, 4971-4978.
DOI 10.1093/cercor/bhx185. PUBMED 28922831.

Javaheri B, Poulet B, Aljazzar A, de Souza R, Piles M, Hopkinson M, Shervill E, Pollard AS, Chan B, Chang Y-M, Orriss IR, Lee PD, Pitsillides AA. (2017) Stable sulforaphane protects against gait anomalies and modifies bone microarchitecture in the spontaneous STR/Ort model of osteoarthritis. Bone. 103, 308-317.
DOI 10.1016/j.bone.2017.07.028  PMCID PMC5571892

McCann CJ, Cooper JE, Natarajan D, Jevans B, Burnett LE, Burns AJ, Thapar N (2017) Transplantation of enteric nervous system stem cells rescues nitric oxide synthase deficient mouse colon. Nature Communications 8, 15937.
DOI 10.1038/ncomms15937. PUBMED 28671186.

Chatzeli L, Gaete M, Tucker AS (2017) Fgf10 and Sox9 are essential for the establishment of distal progenitor cells during mouse salivary gland development. Development 144, 2294-2305.
DOI 10.1242/dev.146019. PUBMED 28506998.

Hockman D,  Burns AJ, Schlosser G, Gates KP, Jevans B,  Mongera A, Fisher S, Unlu G, Knapik EW, Kaufman CK, Mosimann C, Zon LI, Lancman JJ, Dong PDS, Lickert H, Tucker AS, Baker CVH (2017) Evolution of the hypoxia-sensitive cells involved in amniote respiratory reflexes. E Life 6, e21231.
DOI 10.7554/eLife.21231.

Pollard AS, Charlton BG, Hutchinson JR, Gustafsson T, McGonnell IM, Timmons JA, Pitsillides AA (2017) Limb proportions show developmental plasticity in response to embryo movement. Scientific Reports 7, 41926.
DOI 10.1038/srep41926. PUBMED 28165010

Goldspink DA,  Rookyard C,  Tyrrell BJ, Gadsby J, Perkins J, Lund EK,  Galjart N, Thomas P, Wileman T,    Mogensen, MM (2017)  Ninein is essential for apico-basal microtubule formation and CLIP-170 facilitates its redeployment to non-centrosomal microtubule organizing centres. Open Biology 7, 160274.
DOI 10.1098/rsob.160274 PMC5356440

Pollard AS, Boyd S, McGonnell IM, Pitsillides AA (2017) The role of embryo movement in the development of the furcula. Journal of Anatomy 230, 435-443.
DOI 10.1111/joa.12571. PUBMED 27921302  

Thomson AK, Somers E, Powis RA, Shorrock HK, Murphy K, Swoboda KJ, Gillingwater TH, Parson SH (2017) Survival of motor neurone protein is required for normal postnatal development of the spleen. Journal of Anatomy 230, 337-346.
DOI 10.1111/joa.12546. PUBMED 27726134

Harkin LF, Lindsay SJ, Xu YB, Alzu'bi A, Ferrara A, Gullon EA, James OG, Clowry GJ (2017) Neurexins 1-3 each have a distinct pattern of expression in the early developing human cerebral cortex. Cerebral Cortex 27, 216-232.
DOI 10.1093/cercor/bhw394. PMC5654756

Donovan APA, Basson MA (2017) The neuroanatomy of autism - a developmental perspective. Journal of Anatomy 230, 4-15.
DOI 10.1111/joa.12542. PUBMED 27620360.